https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52405 Wed 28 Feb 2024 15:54:25 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45122 P = 0.014). The incidence of HDL-C hypolipidemia in the over 65 years old group was higher than that of the ≤65 age group (HR = 1.276, P = 0.009). The incidence of HDL-C hypolipidemia increased with increasing BMI (HR = 1.030, P = 0.002), TG (HR = 1.321, P = 0.001) and UN (HR = 1.054, P = 0.019), while falling with increasing HDL-C in the baseline year (HR = 0.002, P< 0.001). Conclusions: Men, aged over 65, with high BMI were at the highest risk of developing HDL-C hypolipidemia. Measures should be taken to prevent HDL-C hypolipidemia even for healthy urban adults whose blood biochemical indicators were in the normal range when their level of TG, UN and HDL-C are closed to the border of the normal value range.]]> Wed 26 Oct 2022 12:46:26 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:29593 Wed 24 Nov 2021 15:52:55 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33196 Wed 12 Sep 2018 11:28:03 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:26622 Wed 11 Apr 2018 15:14:56 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7837 Wed 11 Apr 2018 15:08:36 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27387 14.3 years. After adjusting for confounders, diabetic subjects were 49% (cause-specific hazard ratio (_cHR) = 1.49, 95% CI: 1.37, 1.62) more likely to develop kidney failure than non-diabetic subjects. Albuminuria categories A3 and A2 were, respectively, 3.40 (95% CI: 3.07, 3.76) and 1.71 (95% CI: 1.53, 1.92) higher risk of kidney failure when compared to A1. For each albumin category, death rate increased as albuminuria increased particularly in diabetic subjects, which was approximately 2 times higher in A3 compared to A1. Considering GFR category, it gradually increased from G1 to G4 and sharply increased from G4 to G5 in both non-diabetic and diabetic subjects. This study has quantified CKD progression in an Asian population within ordinary practice. Diabetic subjects progress through GFR and albuminuria categories and reach kidney failure about twice as rapidly as non-diabetic subjects.]]> Wed 11 Apr 2018 10:07:38 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:14030 Wed 11 Apr 2018 10:05:47 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50848 Wed 09 Aug 2023 09:31:56 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48997 35 cigarettes/day. Lung cancer risk was lower with quitting at any age but remained higher than never-smokers for quitters aged >25y. By age 80y, an estimated 48.3% of current-smokers (41.1% never-smokers) will develop cancer, and 14% will develop lung cancer, including 7.7% currently smoking 1-5 cigarettes/day and 26.4% for >35 cigarettes/day (1.0% never-smokers). Cancer risk for Australian smokers is significant, even for 'light' smokers. These contemporary estimates underpin the need for continued investment in strategies to prevent smoking uptake and facilitate cessation, which remain key to reducing cancer morbidity and mortality worldwide.]]> Wed 03 May 2023 12:03:16 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45662 20 g/day was associated with a 13% (95% CI = 7–20%) increase in the risk of total mortality. Comparable findings were observed for cardiovascular (CV) deaths. With regard to cancer, drinking up to 10 g/day was not associated with either mortality risk reduction or increase, while alcohol intake > 20 g/day was associated with a 22% (95% CI = 10–35%) increased risk of mortality. The association of alcohol with fatal outcomes was similar in men and women, differed somewhat between countries and was more apparent in individuals preferring wine, suggesting that benefits may not be due to ethanol but other ingredients. Mediation analysis showed that high-density lipoprotein cholesterol explained 2.9 and 18.7% of the association between low alcohol intake and total as well as CV mortality, respectively. Conclusions: In comparison with life-time abstainers, consuming less than one drink per day (nadir at 5 g/day) was associated with a reduced risk of total, cardiovascular and other causes mortality, except cancer. Intake of more than two drinks per day was associated with an increased risk of total, cardiovascular and especially cancer mortality.]]> Wed 02 Nov 2022 15:52:10 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:34542 Tue 26 Mar 2019 15:11:01 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47671 Tue 24 Jan 2023 15:54:44 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19941 Tue 18 Aug 2015 11:14:17 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53677 Tue 09 Jan 2024 12:52:55 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18 5 kg over 5 years) were highest for women who quit smoking (odds ratio = 2.94; 95% confidence interval, 2.17, 3.96). There were also independent relationships between the odds of gaining > 5 kg and lower levels of habitual physical activity, more time spent sitting, energy intake (but only in women with BMI > 25 at baseline), menopause transition, and hysterectomy. Discussion: The average weight gain equates with an energy imbalance of only about 10 kcal or 40 kJ per day, which suggests that small sustained changes in the modifiable behavioral variables could prevent further weight gain.]]> Thu 25 Jul 2013 09:10:09 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49346 Thu 11 May 2023 16:31:08 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:35546 Thu 03 Feb 2022 12:19:38 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1449 5 kg over 5 years) were highest for women who quit smoking (odds ratio = 2.94; 95% confidence interval, 2.17, 3.96). There were also independent relationships between the odds of gaining >5 kg and lower levels of habitual physical activity, more time spent sitting, energy intake (but only in women with BMI > 25 at baseline), menopause transition, and hysterectomy. Discussion: The average weight gain equates with an energy imbalance of only about 10 kcal or 40 kJ per day, which suggests that small sustained changes in the modifiable behavioral variables could prevent further weight gain.]]> Sat 24 Mar 2018 08:28:11 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:14553 Sat 24 Mar 2018 08:19:37 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12240 Sat 24 Mar 2018 08:08:12 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19183 Sat 24 Mar 2018 07:55:03 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19193 Sat 24 Mar 2018 07:54:59 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19394 Sat 24 Mar 2018 07:52:05 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:26135 Sat 24 Mar 2018 07:35:27 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44756 Mon 24 Oct 2022 08:42:37 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51177  0.05). Average heavy consumption definitions of tolerance were most strongly associated with persistent AUD (OR = 6.66, P = 0.001; OR = 4.65, P = 0.004) but not associated with new-onset AUD (Ps > 0.05). Conclusions: Initial drink and percentage change thresholds appear to improve the efficacy of change-based tolerance as an indicator for new-onset alcohol use disorder diagnosis in self-report surveys of young adults. When predicting persistent alcohol use disorder, average heavy consumption-based indicators appear to be a better way to measure tolerance than self-reported change-based definitions.]]> Mon 22 Apr 2024 12:31:43 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44067 Mon 10 Oct 2022 08:54:47 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36406 Mon 04 May 2020 13:46:02 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24367 Fri 22 Apr 2022 10:19:59 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52659 Fri 20 Oct 2023 09:09:41 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45762 Fri 04 Nov 2022 11:02:02 AEDT ]]>